Trazodone is a medication that is commonly used to treat anxiety and depression in humans. As many dog owners as there are, many wonder can Trazodone kill a dog.
In this article, we will discuss the potential risks and side effects of trazodone in dogs, and provide some tips on how to use this medication safely.
Can Trazodone Kill A Dog?
While trazodone is generally safe for dogs when used as directed, it can be harmful or even lethal if ingested in large quantities.
Trazodone can cause a wide range of side effects in dogs, including:
- Sedation
- Dizziness
- Dry mouth
- Low blood pressure
In severe cases, trazodone overdose can cause respiratory depression, coma, and death.
If you think your dog has ingested too much trazodone, contact your veterinarian immediately for advice and treatment.
What is Trazodone?
Trazodone is a medication that belongs to a class of drugs known as serotonin agonists.
It is commonly used in humans to treat anxiety and depression, but it can also be used in dogs to treat certain behavioral problems.
Trazodone works by increasing the levels of serotonin in the brain, which can help to improve mood and reduce anxiety.
In dogs, trazodone can be used to treat separation anxiety, fear of loud noises, and other behavioral disorders.
It is available in both oral and injectable forms, and is typically given to dogs once or twice daily.
As with any medication, it’s important to use trazodone as directed by your veterinarian to avoid potential side effects.
Serotonin Syndrome
Trazodone can cause serotonin syndrome in dogs.
Serotonin syndrome is a condition that occurs when the levels of serotonin in the body become too high.

Symptoms of serotonin syndrome in dogs may include agitation, tremors, hyperthermia, and seizures.
In severe cases, serotonin syndrome can be life-threatening and may require immediate medical treatment.
It’s important to use trazodone as directed by your veterinarian to avoid potential side effects.
Also, avoid giving your dog any other medications that may increase serotonin levels.
Examples would be drugs, such as antidepressants or pain medications.
Should Some Dogs NOT Take Trazodone?
Dogs who have certain medical conditions, such as liver or kidney disease, should not take trazodone.
In addition, trazodone should not be given to dogs who are pregnant or nursing, as it can be harmful to the developing puppies.
Your veterinarian will be able to determine if trazodone is safe for your dog and provide guidance on the correct dosage and administration of the medication.
What Dosage of Trazodone Should A Dog Take?
The correct dosage of trazodone for dogs will depend on several factors, including your dog’s age, weight, and the condition being treated.
It’s important to use trazodone as directed by your veterinarian and not to adjust the dosage without their approval.
Trazodone is typically given to dogs once or twice daily. The dosage may be adjusted based on your dog’s response to the medication.
Your vet will be able to provide guidance on the correct dosage and administration of the medication to ensure your dog receives the benefits of the medication without any adverse effects.
How to Give Your Dog Trazodone
Trazodone is typically given to dogs orally, either as a tablet or liquid solution. To administer trazodone to your dog, follow these steps:
- Wash your hands thoroughly with soap and water to remove any dirt or germs.
- Measure out the correct dosage of trazodone as prescribed by your veterinarian.
- If your dog is taking trazodone tablets, place the tablet in the back of your dog’s mouth and gently hold their mouth closed.
- If your dog is taking trazodone liquid, use the measuring syringe or dropper provided to carefully measure out the correct dosage.
- Place the syringe or dropper into your dog’s mouth and gently squeeze the medication into the back of their mouth.
- Hold your dog’s mouth closed and stroke their throat to encourage them to swallow the medication.
- Once your dog has swallowed the medication, give them a small amount of water to help wash the medication down.
How Long Does it Take Trazodone To Work On Dogs?
The amount of time it takes for trazodone to work in dogs will vary depending on the individual dog and the condition being treated.
In general, it may take several days or even weeks for the full effects of trazodone to be seen.
Some dogs may experience improvement in their symptoms within the first few days of treatment, while others may take longer to respond.
It’s important to follow your veterinarian’s instructions and continue giving your dog trazodone as directed, even if you do not see immediate improvement.
If you have concerns about the effectiveness of the medication, contact your veterinarian for advice.
They can provide guidance on how to adjust the dosage or switch to a different medication if needed.
How Will My Dog Act After Taking Trazodone?
The effects of trazodone in dogs will vary depending on the individual dog and the condition being treated.
In general, trazodone can cause sedation and dizziness, so your dog may appear drowsy or less active after taking the medication.
Some dogs may also experience dry mouth or low blood pressure.
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